Don't drink and game, at least not with Oculus Rift on, says inventor and co-founder Palmer Luckey. In an interview with Joystiq, Luckey said that the nausea-inducing effects of virtual reality displays get amplified when intoxicated, and so in the interest of your controller, your sweet pad carpet, or whatever it is in front of you IRL, don't drink and game.
"What happens is, when you get severely intoxicated, you end up throwing up," Luckey said. "One of the reasons for that is that your body knows something is wrong; your reaction time is slow, things seem to blur. And if it gets bad enough, it says 'Wow, I'm screwed up, I need to get whatever it is out of my stomach that's causing this.' The Rift doesn't do that much, but when you stack it on top of someone already being intoxicated, they tend to not enjoy it nearly as much."